产品货号：
Z25366
中文名称：
Raptor/RPTOR抗体
英文名称：
Anti-Raptor/RPTOR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Raptor/RPTOR Antibody |
| 指标别名 | KIAA1303;raptor;RPTOR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | RPTOR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Raptor polyclonal antibody was raised against a 13 amino acid synthetic peptide from near the amino-terminus of human Raptor.The immunogen is located within amino acids 90 - 140 of Raptor. |
| 计算分子量 | 149kDa |
| 成分 | Raptor Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Raptor Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The mammalian Target of Rapamycin (TOR,also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation.Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo.It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation.These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1,proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels.Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif;mutation of this motif prevents the TOR-dependent phosphorylation of these proteins. |
| Uniprot ID | Q8K4Q0 |
| 基因名全称 | Regulatory associated protein of MTOR,complex 1 |
| 蛋白名全称 | Regulatory associated protein of MTOR,complex 1 |
| 推荐稀释比 | Raptor antibody can be used for the detection of Raptor by Western blot at 2 and 4μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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